When confronted with a situation where the “standard” NPV is inappropriate (see article – Part I), one should first identify all the value drivers and the key elements of the business plan for which uncertainty is high. It should then identify all the options for which it has either to mitigate these uncertainties or to react upon their resolution: the option to postpone the investment, to downsize production capacity, to close down capacity, to exit, to increase capacity, to transform itself into another business, etc.
The difficulty in this process is to find the relevant options, the ones bringing value to the project – the ones for which undertaking a real option valuation approach will be worthwhile.
The fact that management can stop a research project whenever the results of a test are negative, that uncertainty about the success of a research programme is high and that the NPV of such a programme is close to zero clearly indicates that a real option valuation approach should be used. The three conditions discussed in the previous article are met. Starting research on a chemical formula today is effectively an option that gives the right to make pre-clinical trials in a few years. These pre-clinical trials are nothing else but a further option giving the right, if they are successful, to make clinical trials. The clinical trials in turn provide yet another option to invest in a production process if they turn out to be positive. Today, valuing research programmes as a portfolio of compounded options is the best way to estimate the real value of an R&D programme.

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